Guangming Zhong Selected Research

1-O-hexadecyl-2-N-methylcarbamol -sn-glycerol-3-phosphocholine

11/2021	The role of an enzymatically inactive CPAF mutant vaccination in Chlamydia muridarum genital tract infection.
12/2017	CPAF selectively degrades chlamydial T cell antigens for inhibiting antigen presentation.
1/2016	The Chlamydia-Secreted Protease CPAF Promotes Chlamydial Survival in the Mouse Lower Genital Tract.
6/2015	Characterization of CPAF critical residues and secretion during Chlamydia trachomatis infection.
11/2013	A T cell epitope-based vaccine protects against chlamydial infection in HLA-DR4 transgenic mice.
9/2011	Localization of Chlamydia trachomatis hypothetical protein CT311 in host cell cytoplasm.
3/2011	Vaccination with the defined chlamydial secreted protein CPAF induces robust protection against female infertility following repeated genital chlamydial challenge.
10/2010	Secretion of the chlamydial virulence factor CPAF requires the Sec-dependent pathway.
10/2010	Autoprocessing and self-activation of the secreted protease CPAF in Chlamydia-infected cells.
9/2010	Immunization with a combination of integral chlamydial antigens and a defined secreted protein induces robust immunity against genital chlamydial challenge.

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Guangming Zhong Research Topics

Disease

76	Infections 01/2022 - 12/2002
7	Infertility (Sterility) 01/2018 - 11/2010
5	Inflammation (Inflammations) 01/2021 - 06/2005
4	Reinfection 05/2020 - 10/2011
3	Reproductive Tract Infections 01/2022 - 11/2017
3	Trachoma 04/2017 - 10/2011
3	Chlamydia Infections 04/2016 - 01/2012
2	Uterine Cervicitis (Cervicitis) 01/2013 - 12/2004
2	Bacterial Sexually Transmitted Diseases (Sexually Transmitted Disease, Bacterial) 12/2009 - 12/2006
1	COVID-19 12/2020
1	Multiple Sclerosis 10/2020
1	Liver Diseases (Liver Disease) 01/2019
1	Non-alcoholic Fatty Liver Disease 01/2019
1	Disease Progression 04/2017
1	Body Weight (Weight, Body) 03/2016
1	Pyelonephritis 08/2013
1	Trichiasis 05/2012
1	Yersinia Infections 01/2012
1	Neglected Diseases 10/2011
1	Persistent Infection 10/2011
1	Female Infertility 03/2011
1	Smallpox (Variola) 01/2011

Drug/Important Bio-Agent (IBA)

24	Proteins (Proteins, Gene)FDA Link 12/2020 - 02/2003
17	VaccinesIBA 01/2022 - 12/2006
16	1-O-hexadecyl-2-N-methylcarbamol -sn-glycerol-3-phosphocholineIBA 11/2021 - 12/2004
15	AntigensIBA 05/2020 - 03/2006
12	AntibodiesIBA 05/2020 - 12/2004
9	Peptide Hydrolases (Proteases)FDA Link 11/2021 - 08/2006
8	CytokinesIBA 06/2015 - 03/2008
4	Interleukin-12 (IL 12)IBA 08/2013 - 12/2006
3	Phosphates (Orthophosphate)IBA 01/2021 - 02/2007
3	HLA-DR4 Antigen (HLA DR4 Antigen)IBA 01/2018 - 12/2006
3	Immune Sera (Antisera)IBA 05/2012 - 05/2009
3	Subunit VaccinesIBA 01/2012 - 08/2010
3	Interleukin-8 (Interleukin 8)IBA 01/2012 - 03/2008
3	Interferon-gamma (Interferon, gamma)IBA 07/2009 - 12/2006
2	Interleukin-17 (Interleukin 17)IBA 01/2022 - 07/2009
2	SolutionsIBA 01/2021 - 12/2009
2	Biomarkers (Surrogate Marker)IBA 05/2020 - 06/2015
2	ProteomeIBA 05/2020 - 05/2012
2	LipidsIBA 01/2019 - 04/2016
2	Interleukin-6 (Interleukin 6)IBA 11/2017 - 03/2016
2	Immunoglobulin A (IgA)IBA 04/2016 - 07/2004
2	Anti-Bacterial Agents (Antibiotics)IBA 03/2016 - 01/2013
2	p38 Mitogen-Activated Protein KinasesIBA 01/2012 - 04/2010
2	Chaperonin 60IBA 09/2011 - 12/2004
2	TARPIBA 09/2010 - 05/2009
2	NF-kappa B (NF-kB)IBA 04/2010 - 06/2005
2	ChemokinesIBA 07/2009 - 03/2008
2	Membrane Proteins (Integral Membrane Proteins)IBA 06/2008 - 12/2004
1	Interleukin-27 (Interleukin 27)IBA 01/2022
1	salicylhydroxamic acid (SHAM)IBA 01/2021
1	BuffersIBA 01/2021
1	Nucleic AcidsIBA 12/2020
1	Pharmaceutical PreparationsIBA 10/2020
1	Sphingosine-1-Phosphate ReceptorsIBA 10/2020
1	Fingolimod Hydrochloride (FTY720)FDA Link 10/2020
1	Interleukin-18 (Interleukin 18)IBA 01/2019
1	PhosphatidylserinesIBA 01/2019
1	InflammasomesIBA 01/2019
1	Histocompatibility Antigens Class IIIBA 01/2018
1	HLA Antigens (Human Leukocyte Antigens)IBA 01/2018
1	Serine Proteases (Serine Protease)IBA 12/2017
1	PC 16IBA 04/2016
1	Phosphatidylcholines (Phosphatidylcholine)IBA 04/2016
1	Phospholipids (Phosphatides)FDA LinkGeneric 04/2016
1	Peroxidase (Myeloperoxidase)IBA 03/2016
1	NADPH Oxidases (NAD(P)H oxidase)IBA 03/2016
1	Complement System Proteins (Complement)IBA 03/2016
1	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2016
1	Cytokine Receptors (Cytokine Receptor)IBA 05/2014
1	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 05/2014
1	Toll-Like Receptor 2IBA 05/2014
1	Pattern Recognition ReceptorsIBA 05/2014
1	Type I Tumor Necrosis Factor ReceptorsIBA 05/2014
1	LuciferasesIBA 01/2014
1	EpitopesIBA 11/2013
1	T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA 11/2013
1	Interleukin-12 Subunit p35IBA 08/2013
1	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketoneIBA 04/2013
1	EnzymesIBA 04/2013
1	Ribonuclease III (RNase III)IBA 04/2013
1	CaspasesIBA 04/2013
1	GlycogenIBA 01/2013
1	Nuclear Localization Signals (Nuclear Localization Signal)IBA 01/2013
1	LactamsIBA 01/2013
1	Amoxicillin (Wymox)FDA LinkGeneric 01/2013
1	Interleukin-5 (Interleukin 5)IBA 01/2012
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 01/2012
1	Azithromycin (Zithromax)FDA LinkGeneric 01/2012
1	Mitogen-Activated Protein KinasesIBA 01/2012
1	Glycogen Phosphorylase (Phosphorylase, Glycogen)IBA 01/2012
1	Virulence Factors (Pathogenicity Factors)IBA 01/2012
1	Attenuated VaccinesIBA 10/2011
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 07/2011
1	PerforinIBA 07/2011
1	Messenger RNA (mRNA)IBA 04/2011
1	Indicators and Reagents (Reagents)IBA 03/2011
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 11/2010
1	Type III Secretion SystemsIBA 10/2010